Mohammed Sayed Aly Mohammed
Rheumatoid arthritis, classified as an immune system disorder, stands as a prevalent condition that presents considerable challenges to healthcare systems worldwide. This study delved into traditional medicine to explore the use of medicinal plants to treat rheumatoid arthritis and immune system disorders in the world. With a focus on ethno pharmacological insights, a comprehensive survey conducted containing 372 participants, including herbalists and patients, to document the local knowledge and practices associated with these conditions. The findings cleared a noteworthy reliance on traditional medicinal knowledge, with a prominent role played by females across different age groups. A diverse spectrum of 88 plant species hailing from 45 distinct families identified, where the Myrtaceae, Oleaceae, and Zingibneraceae families garnered prominence as the most endorsed choices. Zingiber officinale and Curcuma longa emerged as highly favored species, boasting robust anti-inflammatory and immunomodulatory attributes. Nevertheless, the observed variability in dosage utilization underscores the traditional therapeutic paradigms' intricacies. Moreover, some studies identified endemic species such as Allium sativa, Black pepper, Capsicum annum, Cinnamomum verum, Green tea, Lavandula angistifolia, Thymus vulgaris, and Rosmarinus officinallis—ethnopharmacological Relevance. Traditional medicinal plants used worldwide to treat arthritis, especially in developing countries where resources are meager. Herbal plants have utilized since ancient times and are the base for massive bioactive compounds with flaunting therapeutic potential, many advanced drugs that consumed worldwide to treat countless ailments.