Journal of Clinical Immunology Research
- ISSN: 2576-0572
Hamid Reza Edraki and Safora Ghazimorad
Advances in neuro-technology keep advancing at an astounding pace, and at times it seems like we are closer to science fiction than reality. Neurotech is evolving faster than ever, and staying on top of trends is a must for researchers [1]. On May 29, 2017, at the 70th session of the World Health Assembly in Geneva, the World Health Organization (WHO) has unanimously adopted a global plan on dementia—the Global Plan of Action on the Public Health Response to Dementia 2017–2025—that includes targets for the advancement of dementia awareness, risk reduction, diagnosis, care and treatment, support for care partners, and research.
Loss of noradrenaline (NA)-rich afferents from the Locus Coeruleus (LC) ascending to the hippocampal formation has been reported to dramatically affect distinct aspects of cognitive function, in addition to reducing the proliferation of neural progenitors in the dentate gyrus. Here, the hypothesis that reinstating hippocampal noradrenergic neurotransmission with transplanted LC-derived neuroblasts would concurrently normalize both cognitive performance and adult hippocampal neurogenesis was investigated [2]. Although β2-AR agonists may provide therapeutic value in combination with novel treatments for AD [3]. Advanced PET scan for recognition and pre diagnosis the conflict area such as hippocampus with neural biomarkers and Aβ are promoted and helpful.