Journal of Clinical Immunology Research

  • ISSN: 2576-0572

Importance of clinical and laboratory investigations for diagnosis of Covid-19 infections

Abstract

Ihsan Edan Alsaimary, Ali Osama Ali, Ahmed Saad Abdulkhader, Husain Lateef Abd Hashosh

Background: Covid-19 infections was first emergenced in Wuhan city, China, severe acute respiratory syndrome coronavirus 2, which responsible for the pandemic COVID-19, has become a significant health problem all over the world affecting over 2.1 million people globally.
Aim: The current study aimed to investigate serum levels of ESR, ferritin, C-reactive protein (CRP), D-dimer as well as creatinine and neutrophils count in COVID-19 patients, and to clarify the correlation of these parameters with the disease and progression. Forth ESE purposes,
Methods: A (93) patients with COVID-19 (confirmed by polymer as each in reaction and/or CT-scan).
Results: Almost all study population (patients) were subjected the evaluation of serum levels of ESR, ferritin, and CRP Creatinine, D-dimer, as well as and neutrophils, count. COVID-19 patients showed a significant elevation in the levels of all parameters included in study when compared with healthy controls (standard values). We also found that all of ESR ferritin, CRP Creatinine, and D-dimer are significantly associated with severity of the COVID-19symptoms.
Conclusion: CRP and increased neutrophils were also effectively correlated with disease progression. In line with these results, we concluded a proportional correlation between the aforementioned parameters and COVID-19suggesting the uses of these tests to the diagnosis of critical cases.

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