Journal of Clinical Immunology Research
- ISSN: 2576-0572
Akram A Abd, Dawood S Mahdi and Ihsan E. Al Saimary
Coronavirus disease–2019 (COVID-19) was detected in Wuhan, China, in December 2019 and has resulted in a 2% fatality rate. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus that causes this illness, and it is a newly discovered zoonotic strain. TLRs, which identify microbial components originating from invading pathogens, are implicated in the activation of innate responses to SARS-CoV-2 infection as well as the hyper inflammatory phenotype of COVID-19.
Aim: Determine the molecular structure of Toll-like receptor genes and clarify the immune pathogenesis of TLRs associated with covid 19 to provide insight into the role and early detection of covid 19.
Results: The highest age group of patients with covid_19 was (45-54 years) were 26 (29.5%) of all study patients. The most frequent symptom was fever (82.9%) and the least was diarrhea (21.6%). The study found no significant positive effect of smoking and non-smokers.
Conclusion: The most common clinical symptoms of covid_19 were Fever, Headache, Muscle/ body ache and Loss of taste and/ or smell.