Journal of Gynecology and Reproductive Health
- ISSN: 2574-2728
lsayed Nouh M. Aldoush, Mohammed Osman Ali, Rahma Abdo Ahmed Osman, Tibyan Abd Almajed Altaher, Ghanem Mohammed Mahjaf, Ammar abdelmola and Mosab Nouraldein Mohammed Hamad
Background: Pregnancy is a unique physiological event that might have an impact on a woman›s coagulation and fibrinolytic system. Pregnant women and fetuses may be at risk for thrombotic and bleeding problems due to an abnormally hypercoagulable state during diabetic pregnancy. Thus, pregnant women must have regular coagulation tests to keep track of their coagulation and fibrinolytic systems.
Objective: This research was carried out to analyze Prothrombin Time, Activated Partial Thromboplastin Time, and fibrinogen level in diabetic pregnant and normal pregnant women in Shendi town in Almak Nemer hospital during the period from June to November 2021. Materials and Methods: In tri-sodium citrate, 150 venous blood samples total were taken, 100 from diabetic pregnant women as cases and 50 from healthy pregnant women as controls. A questionnaire was employed to gather certain patient-related data. Coagulometer tests were performed on blood samples.
Results: It was found that pregnant women with diabetes had a significant increase in PT and APTT but a minor increase in fibrinogen when compared to the control result. PT and PTT values were insignificant increase with age, number of pregnancies, and thestage of pregnancy.
Conclusions: In diabetic pregnant women, alterations in the levels of coagulation markers were seen. And the coagulation parameter ranges were reported, which can serve as a point of reference for medical professionals to more precisely monitor the coagulation and fibrinolytic system in pregnant diabetic patients