Dr Aishwarya Gadwal, Dr. Vinay Poornima, Dr Griselda P Norhona, Dr Ashvini Kumar, Dr Akshay Reshmi and Dr Vinay BS
Background: In the context of the COVID-19 pandemic, this study investigates the influence of vaccination on patient demographics and clinical outcomes. Exploring disparities aids in refining public health strategies.
Purpose: To investigate and compare demographics, comorbidities, and clinical characteristics between vaccinated and unvaccinated COVID-19 patients.
Methods: This prospective observational study conducted between January 2021 and June 2022, evaluates CT outcomes in COVID-19 patients relative to vaccination status. Data collection encompasses demographics, comorbidities, and clinical details. Two radiologists independently use a CT Severity Score (CTSS) to evaluate pneumonia extent, exploring associations with age, gender, and vaccination status through statistical analyses.
Results: Out of 1020 patients, 220 were excluded. The study analysed data from 800 patients, with 450 vaccinated and 350 unvaccinated. Demographics and comorbidities showed no significant differences between groups. Dyspnoea and sore throat were more frequent in the unvaccinated group (p < 0.05). C-reactive protein levels were consistently elevated in both groups (>80%), indicative of COVID-19 (p > 0.05). These data provide a comprehensive overview of the patient population, highlighting differences in demographics, comorbidities, and clinical characteristics between vaccinated and unvaccinated individuals. There were no noticeable differences in frequency between patients who had received vaccinations and those who had not.
Conclusions: Vaccination status showed no significant correlation with comorbidity, symptom severity, or clinical outcomes. Younger individuals and females, regardless of vaccination status, showed less lung involvement. Lower CT severity scores