Vasanthabharathi Venkataraman and Kalaiselvi Vaithi
Dementia is not a particular condition, but rather a broad term for the reduced ability to recall, reason, or make decisions, which interferes with daily activities. Alzheimer›s disease is the most prevalent type of dementia. Memory loss, forebrain cell death, and cognitive impairment are hallmarks of Alzheimer›s Disease (AD), a neuro degenerative disease that primarily affects the elderly. The main cause of Alzheimer›s disease is the buildup of tau angles within cells and the release of Aβ outside of them, resulting in neuro-inflammation and oxidative stress. A single genetic mutation accounts for less than 5% of cases of Alzheimer›s disease (AD). It is not uncommon for members of these families to start exhibiting symptoms in their 30s or 40s, and they often do so well before they reach the age of 65. Abnormalities in the neurological system, such as neurodegenerative disorders, can be caused by even little mitochondrial dysfunction. Unfortunately, effective neuronal protective medications to prevent AD are few . Therefore, effective medications that target molecular pathways are desperately needed to combat the massive growth of this disease.